Last reviewed: June 3, 2026

MICA: Microglia in vitro CRISPR Atlas

Kampmann Lab (UCSF)

Data typefunctional genomics

Specieshuman

Sample countThousands of gene knockouts

TechnologyCRISPRi, CRISPRa, scRNA-seq

Disease contextControl, Various

Notes

MICA represents a massive functional genomic screen mapping the transcriptomic and phenotypic consequences of knocking out thousands of genes in iPSC-derived human microglia.

Primary publication

CRISPR screens in human iPSC-derived microglia (2022+)

Access dataset

Last reviewed: June 3, 2026