Last reviewed: October 5, 2026
MoMicA: Mouse Microglia Atlas of Alzheimer's Models
Chongqing Medical University and collaborators
Data typeintegrated single-cell and single-nucleus RNA-seq
Speciesmouse
Sample count84,764 microglia integrated from 10 public datasets
TechnologyscRNA-seq, snRNA-seq, hdWGCNA, pseudotime, multiplex immunofluorescence
Disease contextAlzheimer's disease, Amyloidosis, Tauopathy, Control
Notes
Harmonizes major AD mouse models and resolves a trajectory from homeostatic through activated-response and pre-DAM states to DAM. MoMicA is a secondary integration; its source studies remain distributed across Figshare and nine GEO accessions rather than a single new downloadable atlas object.
Primary publication
Comprehensive single-cell transcriptomic atlas of microglia in Alzheimer's disease mouse models (2026)
Sources
- Comprehensive single-cell transcriptomic atlas of microglia in Alzheimer's disease mouse models (2026) · Link
Last reviewed: October 5, 2026