Last reviewed: October 5, 2026
Alector
AL003
TargetCD33
Modalitymonoclonal antibody
IndicationAlzheimer's disease
PhasePhase 1 (Discontinued)
PartnerAbbVie
Trial IDNCT03822208
Registry statusCOMPLETEDVerified 2026-10-05
Notes
AL003 was a monoclonal antibody directed against CD33, designed to block this inhibitory receptor and promote microglial phagocytosis of amyloid beta. The program was discontinued by AbbVie following Phase 1 evaluations.
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Last reviewed: October 5, 2026